Dubinor Ointment

Introduction

Dubinor is a prescription medication that combines three active ingredients: Gabapentin, Diclofenac, and Methyl Salicylate. It is commonly used to provide relief from pain, inflammation, and neuropathic discomfort.

Uses

Dubinor is prescribed to treat a variety of conditions, including:

• Musculoskeletal pain: It can help alleviate pain and reduce inflammation associated with conditions such as arthritis, sprains, and strains.
• Neuropathic pain: It may provide relief from nerve-related pain, such as diabetic neuropathy and postherpetic neuralgia.

Dosage and Administration

• Before applying Dubinor, ensure that the affected area is clean and dry.
• Apply a thin layer of the ointment to the affected area and gently massage it in until absorbed.
• The recommended dosage and frequency of application may vary depending on the severity and location of the pain. Follow your healthcare professional’s instructions for the best results.
• Wash your hands thoroughly after applying the ointment, unless the treated area is on the hands.

Mechanism of Action

Dubinor contains three active ingredients with different mechanisms of action:

• Gabapentin: It works by reducing the abnormal excitement of nerve cells, which can help alleviate neuropathic pain.
• Diclofenac: It belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by reducing the production of certain chemicals in the body that cause pain and inflammation.
• Methyl Salicylate: It has analgesic and anti-inflammatory properties and can provide temporary relief from muscular pain and discomfort.

Side Effects

Common side effects of Dubinor may include skin irritation, redness, or itching at the application site. These side effects are usually mild and temporary. If you experience any persistent or severe side effects, contact your healthcare professional.

Serious side effects are rare but can occur. Seek immediate medical attention if you experience severe allergic reactions, such as difficulty breathing, swelling of the face or throat, or rash with blistering or peeling skin.

Drug Interactions

inform your healthcare professional about all the medications you are taking, including over-the-counter drugs and supplements. Dubinor may interact with certain medications, such as:

• Blood thinners (e.g., Warfarin): The combination of Dubinor and blood thinners may increase the risk of bleeding.
• Other NSAIDs: Concurrent use of Dubinor with other NSAIDs may increase the risk of side effects.
• Antiepileptic drugs: Gabapentin, one of the active ingredients in Dubinor, may interact with other antiepileptic drugs.

Always consult with your healthcare professional before starting or stopping any medications while using Dubinor.

Precautions

Before using Dubinor, consider the following precautions:

• Allergy: If you have a known allergy to any of the active ingredients in the ointment, avoid using it.
• Pregnancy and breastfeeding: Consult with your healthcare professional before using Dubinor if you are pregnant, planning to become pregnant, or breastfeeding.
• Pre-existing conditions: Inform your healthcare professional about any pre-existing medical conditions, such as liver or kidney disease, as it may affect the safe use of the medication.

Storage

Store Dubinor at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not freeze the ointment.

Patient Tips

• Follow the prescribed dosage and application instructions provided by your healthcare professional.
• Do not apply the ointment to broken skin, wounds, or areas with rashes.
• Avoid contact with eyes, mouth, or other mucous membranes. If accidental contact occurs, rinse with water immediately.
• If your symptoms worsen or persist despite using Dubinor, consult your healthcare professional for further evaluation.
• If you miss a dose, apply the ointment as soon as you remember. However, if it is close to the time of your next scheduled dose, skip the missed dose and resume your regular dosing schedule.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Diclofenac: a non-steroidal anti-inflammatory drug (NSAID) for pain and swelling (NHS UK) [Accessed 0 Jun. 2024] (online) Available at:
• Diclofenac 2.32% gel (Health Professionals SmPC) Available at:
• Diclofenac (Drugs.com) [Accessed 28 Jun. 2024] (online) Available at:
• aleve (diclofenac) 1 % topical gel non-steroidal anti-inflammatory agents (nsaid) (OTC) [Accessed 20 Jun. 2024] (online) Available at:
• Diclofenac Topical (arthritis pain) [Accessed 5 Jun. 2024] (online) Available at:
• Hamed R, Mahmoud NN, Alnadi SH, Alkilani AZ, Hussein G. Diclofenac diethylamine nanosystems-loaded bigels for topical delivery: development, rheological characterization, and release studies. Drug Dev Ind Pharm. 2020 Oct;46(10):1705-1715. doi: 10.1080/03639045.2020.1820038. Epub 2020 Sep 18. [Accessed 23 Jun. 2024] Available at: