Esopase L Capsule ER

Introduction

Esopase L ER is a prescription medication that combines two active ingredients: Levosulpiride and Esomeprazole. Levosulpiride belongs to a class of medications called selective dopamine D2 receptor antagonists, while Esomeprazole is a proton pump inhibitor. This combination medication is primarily used to treat conditions related to excessive stomach acid production and gastrointestinal motility disorders.

Uses

Esopase L ER is commonly prescribed for the following conditions:

• Gastroesophageal Reflux Disease (GERD): It helps reduce the symptoms of heartburn, acid reflux, and regurgitation caused by the reflux of stomach acid into the esophagus.
• Dyspepsia: It provides relief from symptoms like bloating, stomach discomfort, and early satiety associated with indigestion.
• Gastric Ulcers and Duodenal Ulcers: It aids in the healing and prevention of ulcers in the stomach and the upper part of the small intestine.
• Gastroparesis: It helps regulate and improve stomach emptying in patients with delayed gastric emptying.

Dosage and Administration

• The dosage of Esopase L ER varies depending on the specific condition being treated and the individual patient’s response.
• It is typically taken orally, with or without food, as directed by your healthcare provider.
• Swallow the capsule whole without crushing or chewing it, as it is formulated as an extended-release capsule.
• Follow the prescribed dosage schedule and do not adjust the dosage without consulting your healthcare provider.

Mechanism of Action

Esopase L ER combines two different medications that work in distinct ways to provide therapeutic benefits:

• Levosulpiride acts as a selective dopamine D2 receptor antagonist, which helps regulate dopamine levels in the brain and gastrointestinal tract. This action enhances gastrointestinal motility and reduces symptoms associated with gastrointestinal disorders.
• Esomeprazole is a proton pump inhibitor that reduces the production of stomach acid by blocking the enzyme responsible for acid secretion. By reducing the amount of acid in the stomach, it helps alleviate symptoms of acid reflux, ulcers, and other related conditions.

Side Effects

Common side effects include:

• Nausea
• Diarrhea
• Headache
• Abdominal pain
• Dizziness

Serious side effects are rare but may include:

• Allergic reactions (rash, itching, swelling)
• Severe abdominal pain
• Black, tarry stools or blood in stools
• Difficulty swallowing
• Unusual bleeding or bruising

If you experience any severe or persistent side effects, or if you have any concerns, contact your healthcare provider immediately.

Drug Interactions

Esopase L ER may interact with certain medications, potentially altering their effectiveness or increasing the risk of side effects. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some common drug interactions include:

• Anticoagulants (blood thinners) like Warfarin
• Antifungal medications like Ketoconazole
• Antiplatelet drugs like Clopidogrel

follow your healthcare provider’s instructions and inform them of any new medications you start or stop while taking Esopase L ER.

Precautions

Before starting Esopase L ER, inform your healthcare provider about any existing medical conditions or allergies you have, as well as any medications you are currently taking. Precautions to consider include:

• Known hypersensitivity or allergy to Levosulpiride, Esomeprazole, or any other ingredients in the medication.
• History of cardiac disorders, liver disease, or renal impairment.
• Pregnancy or breastfeeding: Consult your healthcare provider for guidance on the use of this medication during pregnancy or while breastfeeding.
• Interactions with other medications: Certain medications, including other proton pump inhibitors, may interact with Esopase L ER. Inform your healthcare provider about all medications you are currently taking to avoid potential interactions.

Storage

Patient Tips

• Take Esopase L ER exactly as prescribed by your healthcare provider. Do not skip doses or alter the dosage without consulting them.
• If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• If you have any concerns or questions about the medication or its side effects, contact your healthcare provider.
• Follow a healthy lifestyle and dietary habits, as advised by your healthcare provider, to enhance the effectiveness of the medication.
• Attend all scheduled appointments with your healthcare provider for regular check-ups and monitoring of your condition.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Esomeprazole: medicine to lower stomach acid (NHS UK) [Accessed 18 Jun. 2024] (online) Available at:
• Boots Heartburn and Acid Reflux Control 20mg Gastro-Resistant Capsules (Health Professionals SmPC) Available at:
• Esomeprazole (Drugs.com) [Accessed 3 Jun. 2024] (online) Available at:
• esomeprazole mag-glycerin kit, capsule delayed release and spray (kit, dr spray) (RX) [Accessed 27 Jun. 2024] (online) Available at:
• Omeprazole (MedlinePlus) [Accessed 8 Jun. 2024] (online) Available at:
• Qi Q, Wang R, Liu L, Zhao F, Wang S. Comparative effectiveness and tolerability of esomeprazole and omeprazole in gastro-esophageal reflux disease: A systematic review and meta-analysis. Int J Clin Pharmacol Ther. 2015 Oct;53(10):803-10. doi: 10.5414/CP202396. [Accessed 15 Jun. 2024] Available at: