Fibnib 100mg Soft Gelatin Capsule

Introduction

Fibnib is a prescription medication that contains the active ingredient Nintedanib. It is available under the brand name Fibnib. This medication is primarily used for the treatment of certain lung diseases, including idiopathic pulmonary fibrosis (IPF), a condition characterized by the scarring of lung tissue. Fibnib helps to slow down the progression of IPF and improve lung function.

Uses

Fibnib is prescribed for the treatment of idiopathic pulmonary fibrosis (IPF). It is used to reduce the rate of decline in lung function and improve the overall quality of life in patients with this condition. Idiopathic pulmonary fibrosis is a chronic lung disease that causes the lung tissue to become thick and scarred, leading to difficulty in breathing and reduced lung capacity. Fibnib works by targeting specific pathways involved in the scarring process, helping to slow down the progression of the disease.

Dosage and Administration

Fibnib should be taken exactly as prescribed by your healthcare provider. The recommended dosage is usually one capsule, twice daily, with food. Swallow the capsule whole with a glass of water, and do not crush, chew, or break it. Follow the prescribed dosage and administration instructions to ensure the medication is effective in managing your condition.

Mechanism of Action

The active ingredient in Fibnib, Nintedanib, belongs to a class of medications known as tyrosine kinase inhibitors. It works by blocking certain enzymes that are involved in the scarring process of the lung tissue. By inhibiting these enzymes, Fibnib helps to reduce the production of fibrotic tissue and slow down the progression of idiopathic pulmonary fibrosis. This mechanism of action helps to improve lung function and delay further damage to the lungs.

Side Effects

Common side effects may include nausea, diarrhea, vomiting, abdominal pain, loss of appetite, and weight loss. These side effects are generally mild and may improve over time. However, if they persist or worsen, consult your healthcare provider. In rare cases, Fibnib may cause more serious side effects such as liver problems, bleeding, and blood clots. If you experience any unusual or severe side effects, seek immediate medical attention.

Drug Interactions

Fibnib may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some common drug interactions with Fibnib include strong CYP3A4 inhibitors, such as ketoconazole and clarithromycin, which may increase the levels of Nintedanib in the body. Your healthcare provider will carefully consider these interactions and adjust your treatment plan accordingly.

Precautions

Before starting treatment with Fibnib, inform your healthcare provider about any existing medical conditions or allergies you may have. This medication may not be suitable for everyone, especially those with liver problems, bleeding disorders, or a history of blood clots. Fibnib should be used with caution in patients who are pregnant or breastfeeding, as the safety of the medication during these periods has not been established. Additionally, avoid taking certain medications or substances that may interact with Fibnib, such as grapefruit juice and St. John’s wort.

Storage

Fibnib should be stored at room temperature, away from moisture and heat. Keep the medication in its original container, tightly closed, and out of reach of children. Do not use Fibnib if the packaging is damaged or if the expiration date has passed. If you have any unused or expired medication, consult your healthcare provider or pharmacist for proper disposal instructions.

Patient Tips

• Take Fibnib exactly as prescribed by your healthcare provider, at the same time each day, and with food.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not double the dose to make up for a missed one.
• attend regular follow-up appointments with your healthcare provider to monitor your progress and adjust your treatment plan if necessary.
• If you experience any new or worsening symptoms while taking Fibnib, such as shortness of breath or chest pain, contact your healthcare provider immediately.
• Avoid excessive alcohol consumption while taking this medication, as it may increase the risk of liver problems.
• If you have any questions or concerns about Fibnib or your treatment plan, do not hesitate to consult your healthcare provider or pharmacist for more information.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Ofev 100 mg soft capsules (Health Professionals SmPC) Available at:
• Nintedanib (Drugs.com) [Accessed 20 Jun. 2024] (online) Available at:
• nintedanib capsule (RX) [Accessed 28 Jun. 2024] (online) Available at:
• Nintedanib (MedlinePlus) [Accessed 8 Jun. 2024] (online) Available at:
• Distler O, Highland KB, Gahlemann M, Azuma A, Fischer A, Mayes MD, Raghu G, Sauter W, Girard M, Alves M, Clerisme-Beaty E, Stowasser S, Tetzlaff K, Kuwana M, Maher TM; SENSCIS Trial Investigators. Nintedanib for Systemic Sclerosis-Associated Interstitial Lung Disease. N Engl J Med. 2019 Jun 27;380(26):2518-2528. doi: 10.1056/NEJMoa1903076. Epub 2019 May 20. [Accessed 27 Jun. 2024] Available at: