Itrostred-TF Cream

Introduction

Itrostred-TF is a topical medication that combines the active ingredients Itraconazole and Terbinafine. It is used to treat fungal infections of the skin, including athlete’s foot, jock itch, and ringworm. This cream is available under the brand name Itrostred-TF.

Uses

Itrostred-TF is prescribed for the treatment of various fungal infections of the skin caused by dermatophyte fungi. These include conditions such as athlete’s foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis). It is also effective in treating fungal infections of the nails (onychomycosis).

Dosage and Administration

Before applying Itrostred-TF, thoroughly clean and dry the affected area. Apply a thin layer of the cream to the affected skin and gently massage it in until it is fully absorbed. The cream should be applied once or twice daily, as directed by your healthcare provider. Continue using the cream for the full duration of the prescribed treatment, even if symptoms improve.

Mechanism of Action

Itrostred-TF works by inhibiting the growth of fungi that cause skin infections. The active ingredients, Itraconazole and Terbinafine, work in different ways to disrupt the normal functioning of the fungi. Itraconazole interferes with the synthesis of ergosterol, an essential component of the fungal cell membrane, while Terbinafine inhibits an enzyme called squalene epoxidase, which is necessary for the production of ergosterol. By disrupting the production of ergosterol, Itrostred-TF weakens the fungal cell membrane and ultimately leads to the death of the fungus.

Side Effects

Common side effects may include skin irritation, redness, itching, or a burning sensation at the application site. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, such as severe skin irritation or an allergic reaction (e.g., rash, swelling, difficulty breathing), seek medical attention immediately.

Drug Interactions

Itrostred-TF may interact with certain medications, including other antifungal drugs and drugs that are metabolized by the liver. Inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal products, to avoid any potential drug interactions. They can provide guidance on the safe use of Itrostred-TF in combination with other medications.

Precautions

Before using Itrostred-TF, inform your healthcare provider about any known allergies or sensitivities to medications. Additionally, let your healthcare provider know if you have any pre-existing medical conditions, especially liver disease. Itrostred-TF should not be used in individuals with a known hypersensitivity to Itraconazole, Terbinafine, or any other components of the cream.

Storage

Itrostred-TF should be stored at room temperature, away from excessive heat or moisture. Keep the cream out of the reach of children and pets. Do not freeze the cream. Check the expiration date on the packaging and do not use the cream if it has expired.

Patient Tips

• Follow the instructions provided by your healthcare provider regarding the application of Itrostred-TF.
• Wash your hands before and after applying the cream to prevent the spread of infection.
• Avoid contact with eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water.
• If no improvement is seen after several weeks of treatment or if the condition worsens, contact your healthcare provider.
• Complete the full course of treatment, even if symptoms improve, to ensure effective eradication of the fungal infection.
• If you have any questions or concerns about the use of Itrostred-TF, consult your healthcare provider for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Terbinafine: a medicine to treat fungal skin infections (NHS UK) [Accessed 16 Jun. 2024] (online) Available at:
• Itraconazole 10 mg/ml Concentrate and Solvent for Solution for Infusion (Health Professionals SmPC) Available at:
• Itraconazole (Drugs.com) [Accessed 9 Jun. 2024] (online) Available at:
• itraconazole (RX) [Accessed 4 Jun. 2024] (online) Available at:
• Itraconazole (MedlinePlus) [Accessed 26 Jun. 2024] (online) Available at:
• Piérard GE, Arrese JE, Piérard-Franchimont C. Itraconazole. Expert Opin Pharmacother. 2000 Jan;1(2):287-304. doi: 10.1517/14656566.1.2.287. [Accessed 25 Jun. 2024] Available at: