Megaglim-NT Tablet SR

Introduction

Megaglim-NT SR is a prescription medication that combines two active ingredients: Pregabalin and Nortriptyline. Pregabalin and Nortriptyline are both widely used in the management of certain types of chronic pain, including neuropathic pain. This medication is available in tablet form and is typically prescribed under the brand name Megaglim-NT SR.

Uses

Megaglim-NT SR is primarily prescribed to treat chronic pain conditions, particularly those associated with nerve damage. It is commonly used to manage neuropathic pain caused by conditions such as diabetic neuropathy, postherpetic neuralgia, and fibromyalgia. This medication may also be prescribed for other conditions as determined by a healthcare professional.

Dosage and Administration

The dosage of Megaglim-NT SR will vary depending on the individual patient and their specific condition. Follow the instructions provided by your healthcare professional. Generally, the initial recommended dose is one tablet per day, usually taken in the evening. However, your healthcare provider may adjust the dose as necessary to achieve the desired therapeutic effect. It is important not to exceed the prescribed dosage without consulting your healthcare professional.

Megaglim-NT SR should be taken with or without food, as directed by your healthcare provider. Swallow the tablet whole with a glass of water; do not crush, chew, or break the tablet.

Mechanism of Action

Pregabalin, one of the active ingredients in Megaglim-NT SR, works by reducing the release of certain neurotransmitters in the brain. This helps to decrease the abnormal electrical activity in the brain that can cause seizures and nerve pain. Nortriptyline, the other active ingredient, belongs to a class of medications called tricyclic antidepressants. It works by increasing the levels of certain chemicals in the brain, which helps to alleviate pain and improve mood.

Side Effects

Common side effects may include dizziness, drowsiness, dry mouth, blurred vision, constipation, and weight gain. These side effects are usually mild and go away on their own. However, if they persist or become bothersome, consult your healthcare professional.

In rare cases, Megaglim-NT SR may cause more serious side effects, such as changes in mood or behavior, suicidal thoughts, allergic reactions, or severe skin reactions. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Megaglim-NT SR may interact with other medications, including certain antidepressants, sedatives, and medications that affect blood clotting. Inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions. Your healthcare provider will evaluate the safety and suitability of Megaglim-NT SR in combination with other medications.

Precautions

Before taking Megaglim-NT SR, inform your healthcare professional about any pre-existing medical conditions, such as a history of mental health disorders, seizures, or heart problems. This medication may not be suitable for everyone, and your healthcare provider will assess the potential risks and benefits before prescribing it.

Megaglim-NT SR is contraindicated in individuals with a known hypersensitivity to Pregabalin, Nortriptyline, or any of the inactive ingredients in the formulation. It should not be used in combination with monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing MAOIs.

Storage

Megaglim-NT SR should be stored at room temperature, away from excessive heat, moisture, and light. Keep the medication out of the reach of children and pets. Do not use Megaglim-NT SR beyond the expiration date printed on the packaging.

Patient Tips

• Follow the dosage instructions provided by your healthcare professional and do not exceed the prescribed dose.
• Take Megaglim-NT SR regularly to achieve the best results. Do not skip doses.
• If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• Do not abruptly stop taking Megaglim-NT SR without consulting your healthcare professional, as this may lead to withdrawal symptoms.
• Avoid alcohol while taking this medication, as it may increase the risk of side effects.
• If you have any concerns or questions about Megaglim-NT SR or its usage, consult your healthcare professional for guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Nortriptyline: a medicine used to treat nerve pain and depression (NHS UK) [Accessed 2 Jun. 2024] (online) Available at:
• Nortriptyline 10 mg Film-coated Tablets (Health Professionals SmPC) Available at:
• Nortriptyline (Drugs.com) [Accessed 0 Jun. 2024] (online) Available at:
• nortriptyline hcl (RX) [Accessed 14 Jun. 2024] (online) Available at:
• Nortriptyline (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
• Rubin EH, Biggs JT, Preskorn SH. Nortriptyline pharmacokinetics and plasma levels: implications for clinical practice. J Clin Psychiatry. 1985 Oct;46(10):418-24. [Accessed 9 Jun. 2024] Available at: