Introduction
Nafodil is a prescription medication that contains the active ingredient Naftopidil. It is available under the brand name Nafodil. This medication is primarily used to treat symptoms associated with benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland.
Uses
Nafodil is prescribed to alleviate the urinary symptoms associated with benign prostatic hyperplasia (BPH). These symptoms may include difficulty in urination, frequent urination, urgency to urinate, weak urine flow, and incomplete emptying of the bladder. By targeting the smooth muscles in the prostate gland and the bladder neck, Nafodil helps to improve urinary flow and relieve these symptoms.
Dosage and Administration
The dosage of Nafodil may vary depending on the individual’s age, medical condition, and response to treatment. Follow the instructions provided by your healthcare professional. Typically, the recommended dose for adults is one tablet taken orally, once daily. Take the tablet with a full glass of water and preferably after a meal to minimize the chances of stomach upset.
Mechanism of Action
Naftopidil, the active ingredient in Nafodil, belongs to a class of medications called alpha-blockers. It works by selectively blocking alpha-1 adrenergic receptors in the smooth muscles of the prostate gland and the bladder neck. By doing so, it relaxes these muscles, relieving the pressure on the urethra and facilitating smooth urine flow. This mechanism of action helps to alleviate the urinary symptoms associated with benign prostatic hyperplasia (BPH).
Side Effects
Common side effects may include dizziness, headache, fatigue, nasal congestion, and gastrointestinal disturbances such as nausea, vomiting, or diarrhea. These side effects are usually mild and temporary.
In rare cases, more serious side effects may occur. These may include a rapid or irregular heartbeat, severe dizziness or fainting, difficulty breathing, swelling of the hands or feet, or severe allergic reactions. If you experience any of these serious side effects, seek immediate medical attention.
Drug Interactions
Nafodil may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.
Some medications that may interact with Nafodil include other alpha-blockers, antihypertensive medications, and medications that affect liver enzymes. Your healthcare professional will consider these potential interactions when prescribing Nafodil and may adjust the dosage or recommend alternative medications if necessary.
Precautions
Before starting treatment with Nafodil, inform your healthcare professional about any existing medical conditions, including liver or kidney problems, low blood pressure, heart disease, or any allergies you may have. This information will help your healthcare professional determine if Nafodil is suitable for you.
Nafodil should be used with caution in individuals with severe liver or kidney impairment, as the medication may be cleared from the body more slowly, leading to an increased risk of side effects. Follow your healthcare professional’s instructions and undergo regular check-ups to monitor your response to the medication.
Storage
Nafodil should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use Nafodil after the expiration date printed on the packaging. If you have any expired or unused medication, consult your pharmacist or healthcare professional for proper disposal methods.
Patient Tips
- Take the medication exactly as prescribed by your healthcare professional.
- If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Do not take more than the prescribed dose of Nafodil.
- Avoid activities that require alertness, such as driving or operating machinery, if you experience dizziness or drowsiness while taking this medication.
- Inform your healthcare professional if you experience any new or worsening symptoms while taking Nafodil.
- Attend regular follow-up appointments with your healthcare professional to monitor your response to the medication and address any concerns or questions you may have.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Mecamylamine (Professional Patient Advice) Professional Information (A-Z Drug Facts) (Drugs.com) [Accessed 20 Jun. 2024] (online) Available at:
- Castiglione F, Benigni F, Briganti A, Salonia A, Villa L, Nini A, Di Trapani E, Capitanio U, Hedlund P, Montorsi F. Naftopidil for the treatment of benign prostate hyperplasia: a systematic review. Curr Med Res Opin. 2014 Apr;30(4):719-32. doi: 10.1185/03007995.2013.861813. Epub 2013 Dec 18. [Accessed 10 Jun. 2024] Available at:
- Nitroprusside (Professional Patient Advice) Professional Information (A-Z Drug Facts) (Drugs.com) [Accessed 14 Jun. 2024] (online) Available at:
- Garimella PS, Fink HA, Macdonald R, Wilt TJ. Naftopidil for the treatment of lower urinary tract symptoms compatible with benign prostatic hyperplasia. Cochrane Database Syst Rev. 2009 Oct 7;(4):CD007360. doi: 10.1002/14651858.CD007360.pub2. [Accessed 21 Jun. 2024] Available at:
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