Niftran TM 100mg Capsule

Introduction

Niftran TM is a prescription medication that contains the active ingredient Nitrofurantoin. It is commonly prescribed under the brand name Niftran TM. This medication is primarily used to treat urinary tract infections caused by certain bacteria.

Uses

Niftran TM is prescribed to treat urinary tract infections, including cystitis (inflammation of the bladder) and pyelonephritis (kidney infection). It works by stopping the growth of bacteria that cause these infections, helping to relieve symptoms and prevent further complications.

Dosage and Administration

The dosage of Niftran TM may vary depending on the severity of the infection and individual patient factors. Follow your healthcare provider’s instructions and take the medication exactly as prescribed. Typically, the recommended adult dosage for urinary tract infections is 100 mg to 200 mg taken twice daily for 7 to 10 days. The capsules should be swallowed whole with a glass of water, preferably with food or milk to reduce the chance of stomach upset.

Mechanism of Action

Nitrofurantoin, the active ingredient in Niftran TM, works by interfering with the bacterial enzymes responsible for the synthesis of DNA, RNA, and proteins. This disruption impairs the growth and reproduction of bacteria, thereby inhibiting their ability to cause infection. Nitrofurantoin is mainly active against bacteria that commonly cause urinary tract infections.

Side Effects

Niftran TM may cause some side effects in certain individuals. Common side effects include nausea, vomiting, loss of appetite, and diarrhea. If these side effects persist or worsen, consult your healthcare provider. Serious side effects are rare but may include severe allergic reactions, lung problems, and liver damage. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. Nitrofurantoin may interact with certain medications, including antacids containing magnesium trisilicate, which may reduce its effectiveness. Additionally, Nitrofurantoin may interact with other antibiotics, such as quinolones or sulfa drugs. Your healthcare provider will be able to advise you on any potential drug interactions.

Precautions

Before taking Niftran TM, inform your healthcare provider if you have any allergies, especially to Nitrofurantoin or other antibiotics. Disclose your medical history, especially if you have kidney problems or a history of liver disease. This medication should be used with caution in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Niftran TM may also cause discoloration of urine, which is normal and not a cause for concern.

Storage

Niftran TM should be stored at room temperature, away from heat, moisture, and light. Keep the medication out of reach of children and pets. Do not use Niftran TM after the expiration date printed on the packaging.

Patient Tips

• Take Niftran TM with food or milk to reduce the chance of stomach upset.
• Complete the full course of treatment as prescribed by your healthcare provider, even if you start feeling better before the course is finished.
• Drink plenty of fluids while taking this medication to help flush out the bacteria from your urinary tract.
• If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• If you have any questions or concerns about Niftran TM, consult your healthcare provider for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Nitrofurantoin: antibiotic to treat bacterial infections (NHS UK) [Accessed 15 Jun. 2024] (online) Available at:
• MacroBID100mg Prolonged-release Capsules (Health Professionals SmPC) Available at:
• Nitrofurantoin (Drugs.com) [Accessed 15 Jun. 2024] (online) Available at:
• nitrofurantoin (RX) [Accessed 2 Jun. 2024] (online) Available at:
• Nitrofurantoin (MedlinePlus) [Accessed 2 Jun. 2024] (online) Available at:
• Mahdizade Ari M, Dashtbin S, Ghasemi F, Shahroodian S, Kiani P, Bafandeh E, Darbandi T, Ghanavati R, Darbandi A. Nitrofurantoin: properties and potential in treatment of urinary tract infection: a narrative review. Front Cell Infect Microbiol. 2023 Jul 27;13:1148603. doi: 10.3389/fcimb.2023.1148603. eCollection 2023. [Accessed 30 Jun. 2024] Available at: