Obiholic 5mg Tablet

Introduction

Obiholic is a prescription medication that contains obeticholic acid as its active ingredient. It is available under the brand name Obiholic. Obeticholic acid is a medication that is primarily used for the treatment of a specific liver disease called primary biliary cholangitis (PBC).

Uses

Obiholic is prescribed for the treatment of primary biliary cholangitis (PBC). PBC is a chronic autoimmune liver disease that causes inflammation and damage to the small bile ducts within the liver. Obeticholic acid, the active ingredient in Obiholic, helps to improve liver function and slow down the progression of PBC.

Dosage and Administration

Obiholic is typically taken orally once daily. The recommended dosage may vary depending on the individual patient’s condition and response to treatment. Follow the instructions provided by your healthcare professional and to take the medication as prescribed. Do not adjust the dosage or stop taking the medication without consulting your doctor.

Mechanism of Action

Obeticholic acid, the active ingredient in Obiholic, works by binding to a specific receptor in the liver called farnesoid X receptor (FXR). By activating FXR, obeticholic acid helps to regulate the production and flow of bile acids, which are essential for the digestion and absorption of fats. This mechanism of action helps to reduce the inflammation and damage to the bile ducts in patients with primary biliary cholangitis.

Side Effects

Common side effects may include itching, fatigue, abdominal pain, and constipation. Note that not all patients will experience these side effects, and they may vary in severity.

Serious side effects are rare but can occur. These may include liver problems, such as an increase in liver enzymes or worsening liver function, which may require close monitoring by your healthcare professional. If you experience any unusual or severe side effects, seek medical attention immediately.

Drug Interactions

Obiholic may interact with other medications, including certain cholesterol-lowering drugs, such as statins, or drugs that affect the transport of bile acids, such as bile acid sequestrants. These interactions can affect the effectiveness of both Obiholic and the other medications. Inform your healthcare professional about all the medications you are taking, including prescription, over-the-counter, and herbal products, before starting Obiholic.

Precautions

Before taking Obiholic, inform your healthcare professional about any existing medical conditions or allergies you may have. This includes any history of liver disease, gallbladder disease, or kidney problems. Additionally, inform your doctor about all the medications you are currently taking to ensure there are no potential interactions.

Obiholic should not be used in pregnant women, as it may cause harm to the unborn baby. Use effective contraception while taking this medication and to discuss family planning with your healthcare professional.

Storage

Obiholic should be stored at room temperature, away from moisture and heat. Keep the medication in its original packaging and out of reach of children. Do not use Obiholic if the expiration date on the packaging has passed.

Patient Tips

• Take Obiholic exactly as prescribed by your healthcare professional. Do not adjust the dosage or stop taking the medication without consulting your doctor.
• If you have any questions or concerns about Obiholic, speak with your healthcare professional. They can provide you with the necessary information and guidance.
• attend regular follow-up appointments with your doctor to monitor your condition and response to treatment.
• If you experience any unusual or severe side effects while taking Obiholic, seek medical attention immediately.
• Remember to store Obiholic properly, away from moisture and heat, and out of reach of children.
• If you have any concerns or questions about potential drug interactions, consult your healthcare professional before starting any new medications.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Primary biliary cholangitis (primary biliary cirrhosis) – Treatment (NHS UK) [Accessed 24 Jun. 2024] (online) Available at:
• OCALIVA 10mg film-coated tablets (Health Professionals SmPC) Available at:
• Obeticholic acid (Drugs.com) [Accessed 28 Jun. 2024] (online) Available at:
• obeticholic acid tablet (RX) [Accessed 2 Jun. 2024] (online) Available at:
• Obeticholic Acid (MedlinePlus) [Accessed 19 Jun. 2024] (online) Available at:
• [No authors listed] Obeticholic Acid. 2019 Dec 10. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. [Accessed 20 Jun. 2024] Available at: