Introduction
Percompa is a prescription medication that contains the active ingredient perampanel. It is available under the brand name Percompa. This medication is primarily used in the treatment of epilepsy.
Uses
Percompa is prescribed for the management of partial-onset seizures with or without secondary generalized seizures in patients with epilepsy. It can be used in adults and children above 12 years of age.
Dosage and Administration
The dosage of Percompa should be individualized based on the patient’s age, weight, and medical condition. It is typically started at a low dose and gradually increased as tolerated. The tablets are taken orally with or without food, as directed by the healthcare provider.
Mechanism of Action
Perampanel, the active ingredient in Percompa, works by blocking a specific type of receptor in the brain called the AMPA receptor. By blocking these receptors, perampanel helps to reduce the excessive electrical activity in the brain that can lead to seizures.
Side Effects
Common side effects of Percompa may include dizziness, drowsiness, fatigue, headache, irritability, and balance problems. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, consult a healthcare professional.
Serious side effects of Percompa are rare but may include mood changes, suicidal thoughts, allergic reactions, severe skin reactions, and liver problems. If any of these serious side effects occur, immediate medical attention should be sought.
Drug Interactions
Percompa may interact with other medications, including certain antidepressants, antiepileptic drugs, and central nervous system depressants. These interactions can affect the effectiveness of the medications or increase the risk of side effects. Inform the healthcare provider about all medications being taken to avoid potential interactions.
Precautions
Before using Percompa, inform the healthcare provider about any pre-existing medical conditions, including liver problems or psychiatric disorders. This medication may not be suitable for everyone, and the healthcare provider will assess the risks and benefits before prescribing it.
Percompa should be used with caution in patients with a history of suicidal thoughts or behaviors. Close monitoring may be necessary during treatment.
Storage
Patient Tips
- Take Percompa exactly as prescribed by the healthcare provider. Do not alter the dosage or stop taking the medication without consulting a healthcare professional.
- attend regular check-ups with the healthcare provider to monitor the effectiveness of the medication and any potential side effects.
- Avoid activities that require mental alertness, such as driving or operating heavy machinery, if dizziness or drowsiness occurs.
- If a dose is missed, take it as soon as remembered unless it is close to the next scheduled dose. Do not double the dose to make up for a missed one.
- Inform the healthcare provider about any new or worsening symptoms, such as changes in mood or behavior, during treatment with Percompa.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Fycompa 0.5 mg/ml oral suspension (Health Professionals SmPC) Available at:
- Perampanel (Drugs.com) [Accessed 5 Jun. 2024] (online) Available at:
- perampanel tablet (RX) [Accessed 2 Jun. 2024] (online) Available at:
- Perampanel (MedlinePlus) [Accessed 20 Jun. 2024] (online) Available at:
- Yamamoto T, Gil-Nagel A, Wheless JW, Kim JH, Wechsler RT. Perampanel monotherapy for the treatment of epilepsy: Clinical trial and real-world evidence. Epilepsy Behav. 2022 Nov;136:108885. doi: 10.1016/j.yebeh.2022.108885. Epub 2022 Sep 21. [Accessed 21 Jun. 2024] Available at:
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