Rifaxant-Plus Tablet

Introduction

Rifaxant-Plus is a prescription medication that contains two active ingredients: Rifaximin and Metronidazole. It is available in tablet form and is commonly used to treat certain gastrointestinal infections.

Uses

Rifaxant-Plus is primarily prescribed to treat infections caused by bacteria and certain parasites in the gastrointestinal tract. It is commonly used to treat conditions such as traveler’s diarrhea, bacterial gastroenteritis, and parasitic infections like amebiasis.

Dosage and Administration

The dosage and administration of Rifaxant-Plus should be determined by your healthcare provider, as it may vary depending on the specific condition being treated. Follow your healthcare provider’s instructions carefully.

Generally, Rifaxant-Plus is taken orally with or without food. The tablets should be swallowed whole with a glass of water. It is important not to crush or chew the tablets as this may affect their effectiveness.

Mechanism of Action

Rifaxant-Plus contains two active ingredients: Rifaximin and Metronidazole.

Rifaximin is an antibiotic that works by inhibiting the growth of bacteria in the gastrointestinal tract. It specifically targets certain types of bacteria that can cause infections in the digestive system. By preventing the growth of these bacteria, Rifaximin helps to resolve the infection and alleviate symptoms.

Metronidazole is also an antibiotic that works by killing bacteria and certain parasites that can cause infections in the gastrointestinal tract. It targets the DNA of these microorganisms, disrupting their normal functioning and leading to their death.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, and headache. These side effects are generally mild and go away on their own.

However, be aware of serious side effects that may occur. If you experience any of the following symptoms, seek medical attention immediately: severe abdominal pain, persistent diarrhea, fever, bloody stools, or signs of an allergic reaction such as rash, itching, swelling, or difficulty breathing.

Drug Interactions

Rifaxant-Plus may interact with certain medications, so inform your healthcare provider about all the medications you are currently taking. Some common drug interactions include:

• Warfarin: Rifaxant-Plus may increase the risk of bleeding if taken with warfarin, a blood thinner.
• Phenytoin: Rifaxant-Plus may increase the levels of phenytoin in the blood, which can lead to toxicity.
• Lithium: Rifaxant-Plus may increase the levels of lithium in the blood, which can lead to toxicity.

Discuss all potential drug interactions with your healthcare provider before starting Rifaxant-Plus.

Precautions

Before taking Rifaxant-Plus, inform your healthcare provider about any allergies you may have, as well as any other medications or supplements you are taking.

Rifaxant-Plus should be used with caution in individuals with a history of liver disease or blood disorders. Discuss your medical history with your healthcare provider before starting this medication.

Avoid consuming alcohol while taking Rifaxant-Plus, as it may increase the risk of side effects such as nausea and dizziness.

Storage

Rifaxant-Plus should be stored at room temperature, away from moisture and heat. It should be kept in its original packaging and out of reach of children.

Patient Tips

• Take the medication exactly as prescribed by your healthcare provider. Do not skip doses or stop taking the medication without consulting your healthcare provider.
• If you experience any unusual or bothersome side effects, contact your healthcare provider.
• complete the full course of treatment, even if you start feeling better before the medication is finished.
• If you have any questions or concerns about the medication, do not hesitate to reach out to your healthcare provider for clarification.
• If you are prescribed any other medications while taking Rifaxant-Plus, make sure to inform your healthcare provider to avoid potential drug interactions.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Metronidazole: antibiotic to treat infections (NHS UK) [Accessed 6 Jun. 2024] (online) Available at:
• Acea 0.75% w/w Gel (Health Professionals SmPC) Available at:
• Metronidazole (Drugs.com) [Accessed 26 Jun. 2024] (online) Available at:
• metronidazole (RX) [Accessed 5 Jun. 2024] (online) Available at:
• Metronidazole Injection (MedlinePlus) [Accessed 5 Jun. 2024] (online) Available at:
• Dingsdag SA, Hunter N. Metronidazole: an update on metabolism, structure-cytotoxicity and resistance mechanisms. J Antimicrob Chemother. 2018 Feb 1;73(2):265-279. doi: 10.1093/jac/dkx351. [Accessed 12 Jun. 2024] Available at: