Rifaxigyl-M Oral Suspension

Introduction

Rifaxigyl-M is a prescription medication that contains two active ingredients: Rifaximin and Metronidazole. It is commonly used to treat certain gastrointestinal infections caused by bacteria and parasites.

Uses

Rifaxigyl-M is prescribed to treat a range of conditions, including:

• Traveler’s diarrhea caused by certain bacteria
• Acute diarrhea caused by certain parasites
• Inflammatory bowel disease (IBD) with symptoms of diarrhea
• Bacterial overgrowth in the small intestine

Dosage and Administration

The recommended dosage of Rifaxigyl-M may vary depending on the specific condition being treated. Follow the instructions provided by your healthcare professional or the directions on the prescription label. Generally, the medication is taken orally, usually with or without food. Shake the suspension well before each use to ensure proper mixing of the active ingredients.

Mechanism of Action

Rifaxigyl-M works by targeting the bacteria and parasites that cause gastrointestinal infections. Rifaximin is an antibiotic that works by inhibiting the growth of bacteria, while Metronidazole is an antiprotozoal medication that kills certain parasites. Together, these active ingredients help to eliminate the infection and relieve symptoms.

Side Effects

Common side effects may include:

• Nausea
• Vomiting
• Abdominal pain
• Headache
• Dizziness

If you experience any serious side effects such as severe diarrhea, persistent nausea or vomiting, or signs of an allergic reaction (e.g., rash, itching, swelling), seek medical attention immediately.

Drug Interactions

Rifaxigyl-M may interact with other medications, including:

• Warfarin: The combination of Rifaxigyl-M and warfarin may increase the risk of bleeding. Inform your healthcare professional if you are taking warfarin or any other blood thinners.
• Antacids: Taking antacids with Rifaxigyl-M may decrease the effectiveness of the medication. It is recommended to take Rifaxigyl-M at least 2 hours before or after taking antacids.

Inform your healthcare professional about all the medications, supplements, and herbal products you are currently taking to avoid any potential interactions.

Precautions

Before taking Rifaxigyl-M, discuss any medical conditions or allergies you have with your healthcare professional. They should be aware of:

• Liver disease: Rifaxigyl-M may affect liver function, and caution is advised in patients with pre-existing liver conditions.
• Neurological disorders: Metronidazole may cause neurological side effects, especially at high doses or with prolonged use.
• Allergies: Inform your healthcare professional of any known allergies to rifaximin, metronidazole, or any other medications.

Rifaxigyl-M may interact with certain medications, so inform your healthcare professional about all the medications you are currently taking.

Storage

store Rifaxigyl-M properly to maintain its effectiveness and safety. Keep the suspension in a tightly closed container at room temperature, away from moisture, heat, and direct light. Do not freeze the medication. Always check the expiration date and dispose of any expired medication properly.

Patient Tips

Here are a few additional tips for patients using Rifaxigyl-M:

• Take the medication exactly as prescribed by your healthcare professional and complete the full course of treatment, even if you start feeling better.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• Drink plenty of fluids to stay hydrated while taking Rifaxigyl-M to help manage diarrhea symptoms.
• If you experience any unusual or severe side effects, contact your healthcare professional immediately.
• Avoid consuming alcohol while taking Rifaxigyl-M, as it may increase the risk of certain side effects.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Metronidazole: antibiotic to treat infections (NHS UK) [Accessed 6 Jun. 2024] (online) Available at:
• Acea 0.75% w/w Gel (Health Professionals SmPC) Available at:
• Metronidazole (Drugs.com) [Accessed 26 Jun. 2024] (online) Available at:
• metronidazole (RX) [Accessed 5 Jun. 2024] (online) Available at:
• Metronidazole Injection (MedlinePlus) [Accessed 5 Jun. 2024] (online) Available at:
• Dingsdag SA, Hunter N. Metronidazole: an update on metabolism, structure-cytotoxicity and resistance mechanisms. J Antimicrob Chemother. 2018 Feb 1;73(2):265-279. doi: 10.1093/jac/dkx351. [Accessed 12 Jun. 2024] Available at: