Rozucor B 180mg/40mg Tablet

Introduction

Rozucor B is a medication that combines two active ingredients: Bempedoic acid and Rosuvastatin. Bempedoic acid belongs to a class of medications called ATP citrate lyase inhibitors, while Rosuvastatin is a member of the statin class of drugs. Rozucor B is primarily used to lower cholesterol levels in the blood and reduce the risk of cardiovascular events such as heart attacks and strokes.

Uses

Rozucor B is prescribed to treat high cholesterol levels, a condition known as hypercholesterolemia. It is used in patients who have not achieved their target cholesterol levels through diet and lifestyle modifications alone. This medication helps to lower LDL cholesterol (often referred to as “bad” cholesterol) and triglyceride levels while increasing HDL cholesterol (often referred to as “good” cholesterol”) levels.

Dosage and Administration

The recommended dosage of Rozucor B may vary depending on individual patient characteristics and the severity of their condition. Follow the instructions provided by your healthcare provider or pharmacist. Typically, the initial dose is one tablet taken once daily, with or without food. Your healthcare provider may adjust the dosage based on your response to treatment and your cholesterol levels. Continue taking Rozucor B as prescribed, even if you start feeling better.

Mechanism of Action

Rozucor B works through two different mechanisms to help lower cholesterol levels. Bempedoic acid inhibits an enzyme called ATP citrate lyase, which is involved in the production of cholesterol in the liver. By blocking this enzyme, it reduces the amount of cholesterol synthesized in the body. Rosuvastatin, on the other hand, inhibits an enzyme called HMG-CoA reductase, which is responsible for the production of cholesterol within the liver. By inhibiting this enzyme, Rosuvastatin reduces the amount of cholesterol produced, leading to lower levels in the blood.

Side Effects

Common side effects may include muscle pain, headache, diarrhea, and nausea. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, consult your healthcare provider.

In rare cases, Rozucor B may cause serious side effects such as liver problems, muscle damage, or an allergic reaction. Contact your healthcare provider immediately if you experience symptoms such as unexplained muscle pain, weakness, yellowing of the skin or eyes, dark urine, or difficulty breathing.

Drug Interactions

Rozucor B may interact with certain medications, including but not limited to:

• Other cholesterol-lowering medications (e.g., fibrates, ezetimibe)
• Blood thinners (e.g., warfarin)
• Certain antibiotics (e.g., erythromycin, clarithromycin)
• Antifungal medications (e.g., itraconazole, ketoconazole)
• HIV protease inhibitors (e.g., ritonavir)

inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins, to avoid potential drug interactions.

Precautions

Before starting Rozucor B, inform your healthcare provider about any pre-existing medical conditions, especially liver disease or kidney problems. This medication should be used with caution in patients with these conditions.

Rozucor B is contraindicated in patients who are pregnant, planning to become pregnant, or breastfeeding. It is also not recommended for patients with active liver disease or unexplained persistent elevations in liver function tests.

Additionally, avoid consuming grapefruit or grapefruit juice while taking Rozucor B, as it may increase the risk of side effects.

Storage

Rozucor B should be stored at room temperature, away from direct sunlight and moisture. Keep it out of the reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Follow a healthy diet and exercise regularly to complement the effects of Rozucor B in managing cholesterol levels.
• Attend regular follow-up appointments with your healthcare provider to monitor your cholesterol levels and adjust the dosage if necessary.
• If you forget to take a dose of Rozucor B, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule.
• Do not stop taking Rozucor B without consulting your healthcare provider, as abruptly discontinuing this medication may lead to a rebound effect in cholesterol levels.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

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• Bonora M, Patergnani S, Rimessi A, De Marchi E, Suski JM, Bononi A, Giorgi C, Marchi S, Missiroli S, Poletti F, Wieckowski MR, Pinton P. ATP synthesis and storage. Purinergic Signal. 2012 Sep;8(3):343-57. doi: 10.1007/s11302-012-9305-8. Epub 2012 Apr 12. [Accessed 2 Jun. 2024] Available at: