Sesil 100mg/100mg Suppository

Introduction

Sesil is a prescription medication that contains two active ingredients: Clindamycin and Clotrimazole. Clindamycin is an antibiotic that helps fight bacterial infections, while Clotrimazole is an antifungal medication used to treat fungal infections. This combination medication is primarily used to treat certain vaginal infections caused by bacteria and fungi.

Uses

Sesil is prescribed to treat vaginal infections, including bacterial vaginosis and vaginal yeast infections. Bacterial vaginosis is a common vaginal infection caused by an imbalance of bacteria in the vagina, while vaginal yeast infections are caused by an overgrowth of yeast. Sesil helps to eliminate the bacteria and fungi responsible for these infections, providing relief from symptoms such as itching, burning, and abnormal discharge.

Dosage and Administration

Sesil should be used as directed by your healthcare provider. The usual recommended dosage is one suppository inserted into the vagina once daily, preferably at bedtime, for a prescribed duration of treatment. Carefully follow the instructions provided by your healthcare provider and complete the full course of treatment, even if symptoms improve before the treatment is finished.

To use the suppository, wash your hands thoroughly and remove the suppository from its packaging. Lie on your back with your knees bent and gently insert the suppository into the vagina as far as it will comfortably go. Wash your hands again after insertion. If you have any questions or concerns about the correct use of Sesil, consult your healthcare provider.

Mechanism of Action

Sesil works by combining the antimicrobial effects of Clindamycin and the antifungal effects of Clotrimazole. Clindamycin inhibits the growth of bacteria by interfering with their protein synthesis, ultimately leading to the death of the bacteria. Clotrimazole works by disrupting the cell membranes of fungi, causing them to leak and ultimately leading to their death. Together, these two active ingredients help eliminate the bacteria and fungi responsible for vaginal infections.

Side Effects

Common side effects may include vaginal irritation, itching, burning, or discomfort. These side effects are usually mild and temporary. If any of these side effects persist or worsen, or if you experience any other unusual or severe symptoms, contact your healthcare provider for further guidance.

In rare cases, serious allergic reactions to Sesil may occur. Seek immediate medical attention if you experience symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications may interact with Sesil, potentially affecting its effectiveness or increasing the risk of side effects. Be sure to discuss all your medications with your healthcare provider to ensure safe and effective treatment.

Precautions

Before using Sesil, inform your healthcare provider if you have any known allergies to Clindamycin, Clotrimazole, or any other ingredients in the medication. Additionally, disclose any medical conditions you have, especially if you have a history of gastrointestinal disorders or liver disease.

Note that Sesil is for vaginal use only and should not be taken orally or used in any other way. Avoid contact with the eyes, nose, mouth, or any open wounds.

Storage

Store Sesil at room temperature, away from direct sunlight and moisture. Keep it out of the reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged. Proper storage helps maintain the stability and effectiveness of the medication.

Patient Tips

• Follow the prescribed dosage and treatment duration as instructed by your healthcare provider.
• If using Sesil during menstruation, it is recommended to insert the suppository before going to bed.
• Avoid sexual intercourse during the course of treatment, as it may interfere with the effectiveness of the medication or cause further irritation.
• If you miss a dose, use it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• If you have any questions or concerns about Sesil, consult your healthcare provider for further guidance. They can provide personalized advice based on your specific medical history and needs.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Clotrimazole: medicine used to treat fungal skin infections (NHS UK) [Accessed 25 Jun. 2024] (online) Available at:
• Clindamycin + Benzoyl Peroxide 10mg/g + 50mg/g Gel (Health Professionals SmPC) Available at:
• Clindamycin (Drugs.com) [Accessed 19 Jun. 2024] (online) Available at:
• adapalene 0.15 %-benzoyl peroxide 3.1 %-clindamycin 1.2 % topical gel (RX) [Accessed 0 Jun. 2024] (online) Available at:
• Clindamycin Vaginal (MedlinePlus) [Accessed 12 Jun. 2024] (online) Available at:
• Donaldson M, Goodchild JH. Is clindamycin dangerous? Gen Dent. 2017 Jul-Aug;65(4):12-15. [Accessed 19 Jun. 2024] Available at: