Trilavir E Tablet

Introduction

Trilavir E is a prescription medication that combines three active ingredients: Emtricitabine, Tenofovir disoproxil fumarate, and Efavirenz. It is commonly known by its brand name Trilavir E. This medication is primarily used for the treatment of HIV-1 infection in adults and adolescents aged 12 years and older. It helps to reduce the amount of the virus in the body and improves the immune system’s ability to fight HIV.

Uses

Trilavir E is prescribed for the management of HIV-1 infection. It is used as part of a comprehensive treatment regimen that includes other antiretroviral medications. This medication is essential in controlling the progression of HIV infection, reducing the risk of complications, and improving the overall quality of life for individuals living with HIV.

Dosage and Administration

The recommended dosage of Trilavir E for adults and adolescents aged 12 years and older is one tablet taken orally once daily, preferably on an empty stomach at bedtime. Follow the instructions provided by your healthcare professional or the medication label. Do not alter the dosage or stop taking the medication without consulting your healthcare provider.

Mechanism of Action

Trilavir E works by inhibiting the replication of the HIV virus. Emtricitabine and Tenofovir disoproxil fumarate are nucleoside reverse transcriptase inhibitors (NRTIs) that interfere with the enzyme needed for the virus to replicate its genetic material. Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that blocks a different enzyme required for viral replication. Together, these active ingredients help to suppress the growth of the virus and reduce its impact on the immune system.

Side Effects

Common side effects may include dizziness, headache, trouble sleeping, nausea, diarrhea, and rash. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, such as severe depression, mood changes, liver problems, or signs of an allergic reaction (e.g., swelling, difficulty breathing), seek immediate medical attention.

Drug Interactions

Trilavir E may interact with other medications, including over-the-counter drugs, herbal supplements, and prescription medications. Inform your healthcare provider about all the medications you are currently taking to avoid potential interactions. Some medications that may interact with Trilavir E include rifampin, St. John’s wort, certain anticonvulsants, and certain antifungal medications. Your healthcare provider can provide guidance on managing these interactions.

Precautions

Before taking Trilavir E, inform your healthcare provider about any medical conditions you have, including liver or kidney problems, mental health conditions, or a history of seizures. This medication may not be suitable for everyone, and your healthcare provider will assess the potential risks and benefits in your specific case. Trilavir E may also interact with alcohol and certain substances, so avoid them while taking this medication.

Storage

Trilavir E should be stored at room temperature, away from moisture and heat. Keep it in its original packaging and out of reach of children. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Trilavir E exactly as prescribed by your healthcare provider. Do not skip doses or alter the dosage without consulting them.
• maintain regular follow-up appointments with your healthcare provider to monitor your response to the medication and address any concerns.
• Practice safe sex and take other precautions to prevent the transmission of HIV to others.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• If you have any questions or concerns about Trilavir E or its use, consult your healthcare provider or pharmacist for further information.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

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• efavirenz 400 mg-lamivudine 300 mg-tenofovir disoproxil mg tablet lamivudine (RX) [Accessed 13 Jun. 2024] (online) Available at:
• Efavirenz, Emtricitabine, and Tenofovir (MedlinePlus) [Accessed 19 Jun. 2024] (online) Available at:
• Costa B, Vale N. Efavirenz: History, Development and Future. Biomolecules. 2022 Dec 31;13(1):88. doi: 10.3390/biom13010088. [Accessed 10 Jun. 2024] Available at: