Velpride 75mg/20mg Tablet

Introduction

Velpride is a prescription medication that contains the active ingredients Levosulpiride and Rabeprazole. Levosulpiride is a selective dopamine D2 receptor antagonist, while Rabeprazole belongs to the class of proton pump inhibitors. This combination medication is commonly used to treat various gastrointestinal conditions.

Uses

Velpride is primarily prescribed for the management of conditions such as gastroesophageal reflux disease (GERD), peptic ulcer disease, dyspepsia, and functional dyspepsia. It helps reduce symptoms such as heartburn, acid reflux, and stomach pain.

Dosage and Administration

The dosage of Velpride may vary depending on the individual’s condition and the healthcare professional’s recommendation. Follow the prescribed dosage instructions provided by your doctor. The tablets are typically taken orally with water, before or after meals, as directed by your healthcare provider.

Mechanism of Action

Levosulpiride in Velpride works by blocking the dopamine D2 receptors in the brain, which helps regulate the gastrointestinal motility. It enhances the movement of food through the digestive tract, reducing symptoms of indigestion and reflux. Rabeprazole, on the other hand, inhibits the secretion of stomach acid by blocking the proton pump, thereby reducing acidity.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, dry mouth, and dizziness. Note that not everyone will experience these side effects, and they may vary in severity.

Serious side effects are rare but can occur. If you experience any of the following serious side effects, seek immediate medical attention: severe abdominal pain, persistent vomiting, black or tarry stools, difficulty breathing, or signs of an allergic reaction (such as rash, itching, swelling, or severe dizziness).

Drug Interactions

Velpride may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some common drug interactions include:

• Warfarin: Levosulpiride may increase the risk of bleeding when used with warfarin.
• Methotrexate: Rabeprazole may increase the blood levels of methotrexate, leading to potential toxicity.
• Digoxin: Levosulpiride may increase the concentration of digoxin in the blood.

Consult with your healthcare provider to ensure the safe use of Velpride and to avoid any potential interactions.

Precautions

Before taking Velpride, inform your healthcare provider about any existing medical conditions, allergies, or medications you are currently taking. Certain precautions should be taken into consideration:

• Pregnancy and breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this medication during pregnancy and breastfeeding has not been established.
• Liver or kidney impairment: Velpride should be used with caution in individuals with liver or kidney impairment, as it may require dosage adjustments.
• Allergy: If you have a known allergy to Levosulpiride, Rabeprazole, or any other medications, inform your healthcare provider before starting this medication.
• Other medications: Inform your healthcare provider about all the medications you are currently taking, as there may be potential interactions.

Storage

Patient Tips

• Take Velpride exactly as prescribed by your healthcare provider. Do not exceed the recommended dosage.
• It is advisable to take the medication with a glass of water, before or after meals, as directed by your doctor.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not abruptly stop taking Velpride without consulting your healthcare provider, as it may lead to a worsening of symptoms.
• If you experience any persistent or severe side effects, contact your healthcare provider immediately.
• Follow any additional instructions or recommendations provided by your healthcare provider for optimal results.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Rabeprazole: medicine to lower stomach acid (NHS UK) [Accessed 30 Jun. 2024] (online) Available at:
• PARIET 10mg (Health Professionals SmPC) Available at:
• Levosulpiride (International database) (Drugs.com) [Accessed 7 Jun. 2024] (online) Available at:
• rabeprazole sodium (RX) [Accessed 26 Jun. 2024] (online) Available at:
• Rabeprazole (MedlinePlus) [Accessed 30 Jun. 2024] (online) Available at:
• Arshad A, Irfan M, Inam M, Hussain NHN, Ismail SB. Levosulpiride for Premature Ejaculation: A Systematic Review and Meta-Analysis. Am J Mens Health. 2022 Sep-Oct;16(5):15579883221124832. doi: 10.1177/15579883221124832. [Accessed 8 Jun. 2024] Available at: