Verquvo 2.5mg Tablet

Introduction

Verquvo is a prescription medication that contains the active ingredient Vericiguat. It is available under the brand name Verquvo. This medication is primarily used for the treatment of heart failure in adults.

Uses

Verquvo is prescribed to manage heart failure in patients who have reduced ejection fraction. It helps to improve symptoms and reduce the risk of hospitalization for heart failure.

Dosage and Administration

The recommended dosage of Verquvo is typically determined by your healthcare provider based on your individual needs and medical condition. Follow their instructions carefully. The tablets are usually taken by mouth with or without food, as directed by your doctor. Do not crush or chew the tablets; swallow them whole with a glass of water.

Mechanism of Action

Vericiguat, the active ingredient in Verquvo, belongs to a class of medications called soluble guanylate cyclase (sGC) stimulators. It works by stimulating an enzyme called guanylate cyclase, which increases the production of cyclic guanosine monophosphate (cGMP) in the body. This helps to relax and widen the blood vessels, reduce the workload on the heart, and improve blood flow. By enhancing these processes, Verquvo helps to alleviate symptoms and improve heart function in patients with heart failure.

Side Effects

Common side effects may include headache, dizziness, low blood pressure, and nausea. These side effects are usually mild and go away on their own. However, if you experience any persistent or severe side effects, contact your healthcare provider.

In rare cases, Verquvo may cause more serious side effects, such as allergic reactions, chest pain, irregular heartbeat, or signs of liver problems. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Verquvo may interact with other medications, including but not limited to:

• Nitroglycerin and other nitrates
• Riociguat
• PDE-5 inhibitors (e.g., sildenafil, tadalafil)
• Medications that lower blood pressure

inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid any potential drug interactions.

Precautions

Before starting Verquvo, inform your healthcare provider about any allergies, medical conditions, or medications you are currently taking. This medication may not be suitable for everyone, especially those with severe kidney or liver problems, low blood pressure, or a history of certain heart conditions.

Verquvo should not be used during pregnancy or while breastfeeding, as its safety in these situations has not been established. Discuss the potential risks and benefits with your healthcare provider.

Storage

Verquvo should be stored at room temperature, away from moisture and heat. Keep the medication out of the reach of children and pets. Do not use the tablets if they are past their expiration date.

Patient Tips

• Take Verquvo exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking the medication without consulting them.
• It may take some time for Verquvo to show its full effects. Be patient and continue taking the medication as directed.
• If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• Avoid drinking alcohol while taking Verquvo, as it may increase the risk of side effects.
• If you have any concerns or questions about Verquvo or its use, consult your healthcare provider for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Verquvo 10 mg film-coated tablets (Health Professionals SmPC) Available at:
• Vericiguat (Drugs.com) [Accessed 10 Jun. 2024] (online) Available at:
• vericiguat 10 mg tablet (RX) [Accessed 8 Jun. 2024] (online) Available at:
• Vericiguat (MedlinePlus) [Accessed 13 Jun. 2024] (online) Available at:
• Armstrong PW, Pieske B, Anstrom KJ, Ezekowitz J, Hernandez AF, Butler J, Lam CSP, Ponikowski P, Voors AA, Jia G, McNulty SE, Patel MJ, Roessig L, Koglin J, O’Connor CM; VICTORIA Study Group. Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction. N Engl J Med. 2020 May 14;382(20):1883-1893. doi: 10.1056/NEJMoa1915928. Epub 2020 Mar 28. [Accessed 12 Jun. 2024] Available at: