Introduction
Xarex is a prescription medication that contains the active ingredient Rivaroxaban. It is available under the brand name Xarex. This medication is primarily used to prevent blood clots and reduce the risk of stroke and systemic embolism in patients with certain medical conditions.
Uses
Xarex is prescribed for the following conditions:
- Prevention of deep vein thrombosis (DVT) in patients undergoing hip or knee replacement surgery.
- Treatment and prevention of pulmonary embolism (PE).
- Reduction of the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation.
- Treatment of deep vein thrombosis (DVT) and prevention of recurrent DVT and pulmonary embolism (PE) in patients who have already been treated with an initial dose of a different anticoagulant medication.
Dosage and Administration
The dosage of Xarex may vary depending on the specific medical condition being treated and individual patient factors. Follow the instructions provided by your healthcare professional. Generally, the recommended dose for most conditions is 10 mg taken once daily, with or without food. However, your healthcare professional may adjust the dose based on your specific needs.
Mechanism of Action
Xarex belongs to a class of medications called direct oral anticoagulants. It works by inhibiting a specific protein in the blood called Factor Xa. By inhibiting Factor Xa, Rivaroxaban reduces the ability of the blood to form clots. This helps to prevent the formation of blood clots and reduce the risk of stroke and other serious complications.
Side Effects
Common side effects may include:
- Bleeding, such as nosebleeds or bleeding gums.
- Bruising more easily.
- Dizziness or weakness.
- Headache.
Serious side effects may include:
- Signs of bleeding, such as black or bloody stools, coughing up blood, or vomiting blood.
- Signs of an allergic reaction, such as rash, itching, or swelling.
If you experience any of these serious side effects or any other unusual symptoms, seek medical attention immediately.
Drug Interactions
Xarex may interact with other medications, including over-the-counter drugs, herbal supplements, and prescription medications. Common drug interactions may include:
- Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or aspirin.
- Anticoagulant medications, such as warfarin or heparin.
- Medications that affect liver enzymes, such as ketoconazole or rifampin.
Inform your healthcare professional about all the medications you are currently taking to avoid potential interactions.
Precautions
Before taking Xarex, discuss your medical history and any current medications or supplements with your healthcare professional. Precautions and contraindications may include:
- Hypersensitivity or allergic reactions to Rivaroxaban or any other ingredients in the medication.
- Active bleeding or conditions that increase the risk of bleeding.
- Severe liver disease or impairment.
- Pregnancy or breastfeeding.
Follow your healthcare professional’s guidance and inform them of any changes in your health status or medications.
Storage
Patient Tips
- Take Xarex exactly as prescribed by your healthcare professional.
- Do not stop or change the dosage without consulting your healthcare professional.
- If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Do not double the dose to make up for a missed dose.
- If you have any concerns or questions about the medication, speak with your healthcare professional.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Rivaroxaban: a medicine to help prevent blood clots (NHS UK) [Accessed 8 Jun. 2024] (online) Available at:
- Rivaroxaban 10 mg film-coated tablets (Health Professionals SmPC) Available at:
- Rivaroxaban (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
- rivaroxaban 1 mg/ml oral suspension (RX) [Accessed 11 Jun. 2024] (online) Available at:
- Rivaroxaban (MedlinePlus) [Accessed 0 Jun. 2024] (online) Available at:
- Male C, Lensing AWA, Palumbo JS, Kumar R, Nurmeev I, Hege K, Bonnet D, Connor P, Hooimeijer HL, Torres M, Chan AKC, Kenet G, Holzhauer S, Santamaría A, Amedro P, Chalmers E, Simioni P, Bhat RV, Yee DL, Lvova O, Beyer-Westendorf J, Biss TT, Martinelli I, Saracco P, Peters M, Kállay K, Gauger CA, Massicotte MP, Young G, Pap AF, Majumder M, Smith WT, Heubach JF, Berkowitz SD, Thelen K, Kubitza D, Crowther M, Prins MH, Monagle P; EINSTEIN-Jr Phase 3 Investigators. Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial. Lancet Haematol. 2020 Jan;7(1):e18-e27. doi: 10.1016/S2352-3026(19)30219-4. Epub 2019 Nov 5. [Accessed 0 Jun. 2024] Available at:
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