Introduction
Zifcas O is a prescription medication that combines the active ingredients Cefixime and Ofloxacin. Cefixime is an antibiotic that belongs to the class of drugs known as cephalosporins, while Ofloxacin is a fluoroquinolone antibiotic. This combination medication is primarily used to treat various bacterial infections in adults and children.
Uses
Zifcas O is commonly prescribed for the treatment of respiratory tract infections, such as bronchitis and pneumonia. It is also effective in treating urinary tract infections, including cystitis and pyelonephritis. Additionally, this medication may be prescribed for certain sexually transmitted infections, such as gonorrhea.
Dosage and Administration
The dosage of Zifcas O may vary depending on the severity of the infection and the individual’s age and weight. Follow the instructions provided by your healthcare professional or the guidance on the product label. Generally, the recommended dosage for adults is one tablet taken orally twice daily. For children, the dosage is adjusted based on their weight. Complete the full course of treatment as prescribed, even if symptoms improve before the medication is finished.
Mechanism of Action
Zifcas O works by inhibiting the growth and spread of bacteria in the body. Cefixime acts by interfering with the synthesis of the bacterial cell wall, ultimately leading to cell death. Ofloxacin works by inhibiting the enzyme DNA gyrase, which is essential for bacterial DNA replication and repair. By targeting different mechanisms, the combination of Cefixime and Ofloxacin provides a broad-spectrum antibacterial effect.
Side Effects
Common side effects may include nausea, vomiting, diarrhea, and abdominal pain. These side effects are usually mild and temporary. However, if they persist or worsen, consult your healthcare professional.
Serious side effects are rare but may include severe allergic reactions, such as rash, itching, swelling, or difficulty breathing. If you experience any of these symptoms, seek immediate medical attention.
Drug Interactions
Zifcas O may interact with certain medications and substances. Inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. Some medications, such as antacids containing aluminum or magnesium, may reduce the absorption of Ofloxacin. Additionally, certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), may increase the risk of side effects.
Precautions
Before taking Zifcas O, inform your healthcare professional if you have any allergies, especially to cephalosporin antibiotics or fluoroquinolones. Disclose your medical history, including any kidney or liver problems.
This medication may not be suitable for everyone. It is contraindicated in individuals with a history of hypersensitivity reactions to cephalosporin antibiotics or fluoroquinolones. Additionally, it should be used with caution in pregnant or breastfeeding women.
Storage
Zifcas O should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or shows signs of deterioration.
Patient Tips
- Take Zifcas O with a full glass of water, with or without food, as directed by your healthcare professional.
- If you experience any gastrointestinal upset, taking the medication with food may help alleviate symptoms.
- Complete the full course of treatment, even if you start feeling better before finishing the medication.
- If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Inform your healthcare professional if you develop any new symptoms or if your condition worsens while taking Zifcas O.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- EXOCIN® 3 mg/ml Eye Drops, Solution. (Health Professionals SmPC) Available at:
- Cefixime (Drugs.com) [Accessed 3 Jun. 2024] (online) Available at:
- cefixime (RX) [Accessed 10 Jun. 2024] (online) Available at:
- Cefixime (MedlinePlus) [Accessed 24 Jun. 2024] (online) Available at:
- Stafylis C, Keith K, Mehta S, Tellalian D, Burian P, Millner C, Klausner JD. Clinical Efficacy of Cefixime for the Treatment of Early Syphilis. Clin Infect Dis. 2021 Sep 7;73(5):907-910. doi: 10.1093/cid/ciab187. [Accessed 26 Jun. 2024] Available at:
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