Zonalta 8mg Tablet

Introduction

Zonalta is a prescription medication that contains the active ingredient Endoxifen. It is available under the brand name Zonalta. This medication is primarily used for the treatment of certain types of breast cancer.

Uses

Zonalta is prescribed to patients with hormone receptor-positive breast cancer. It is used as adjuvant therapy, meaning it is given after primary treatment such as surgery or radiation, to reduce the risk of cancer recurrence. This medication is also used in the treatment of metastatic breast cancer.

Dosage and Administration

The dosage of Zonalta may vary depending on the specific needs of the patient and the stage of breast cancer being treated. Follow the instructions provided by your healthcare provider. Generally, the recommended dose is one tablet taken orally once daily, with or without food. Take the medication at the same time each day to maintain consistent levels in the body.

Mechanism of Action

Endoxifen, the active ingredient in Zonalta, works by blocking the effects of estrogen in breast tissue. In hormone receptor-positive breast cancer, estrogen can fuel the growth of cancer cells. Endoxifen binds to estrogen receptors, preventing estrogen from binding and activating these receptors. By inhibiting the effects of estrogen, Zonalta helps to slow down or stop the growth of breast cancer cells.

Side Effects

Common side effects may include hot flashes, fatigue, nausea, and joint pain. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen. Inform your healthcare provider.

In some cases, Zonalta may cause more serious side effects. These can include blood clots, stroke, or uterine cancer. If you experience any severe or persistent side effects, such as sudden shortness of breath, chest pain, severe headache, or abnormal vaginal bleeding, seek immediate medical attention.

Drug Interactions

Zonalta may interact with other medications, including selective serotonin reuptake inhibitors (SSRIs), blood thinners, and certain antifungal medications. These interactions can affect the effectiveness of Zonalta or increase the risk of side effects. Inform your healthcare provider about all the medications you are taking, including over-the-counter drugs and supplements, to avoid potential drug interactions.

Precautions

Before starting treatment with Zonalta, inform your healthcare provider about any medical conditions you have, especially if you have a history of blood clots, stroke, or liver disease. This medication may not be suitable for everyone, and your healthcare provider will evaluate the potential risks and benefits before prescribing it to you.

Zonalta is not recommended for use during pregnancy or breastfeeding, as it may harm the developing fetus or infant. Use effective contraception while taking this medication.

Storage

Zonalta should be stored at room temperature, away from moisture and heat. Keep it out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Zonalta exactly as prescribed by your healthcare provider. Do not alter the dosage or stop taking the medication without consulting your doctor.
• If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• attend all follow-up appointments with your healthcare provider to monitor your response to the medication and manage any potential side effects.
• Inform your healthcare provider about any new or worsening symptoms, as it may be necessary to adjust your treatment plan.
• Zonalta may cause dizziness or drowsiness. Avoid driving or operating machinery until you know how this medication affects you.
• Follow a healthy lifestyle, including a balanced diet and regular exercise, to support your overall well-being during treatment.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Tamoxifen Monograph for Professionals (Drugs.com) [Accessed 19 Jun. 2024] (online) Available at:
• Jayaraman S, Reid JM, Hawse JR, Goetz MP. Endoxifen, an Estrogen Receptor Targeted Therapy: From Bench to Bedside. Endocrinology. 2021 Dec 1;162(12):bqab191. doi: 10.1210/endocr/bqab191. [Accessed 11 Jun. 2024] Available at:
• Pexeva: Package Insert / Prescribing Information Prescribing Information (Drugs.com) [Accessed 8 Jun. 2024] (online) Available at:
• Paroxetine Oral Suspension: Package Insert Prescribing Information (Drugs.com) [Accessed 7 Jun. 2024] (online) Available at: