Bivalirudin

Bivalirudin is an anticoagulant medication used to prevent blood clots from forming or growing in size. It is a synthetic version of a naturally occurring protein called hirudin, which is derived from the saliva of the medicinal leech. Bivalirudin works by inhibiting the activity of thrombin, an enzyme that plays a crucial role in the clotting process.
Bivalirudin is primarily used during percutaneous coronary interventions (PCIs), which are medical procedures to open blocked or narrowed coronary arteries. By reducing the risk of blood clots, bivalirudin helps ensure the success of these procedures and lowers the chances of complications, such as heart attacks or strokes. Additionally, it may be used in patients with unstable angina or during cardiac surgery to prevent blood clot formation.
As an anticoagulant, bivalirudin acts rapidly and has a short half-life, which means it starts working quickly and its effects wear off relatively soon after it is administered. This makes it a valuable option for patients who require rapid anticoagulation during medical procedures, as it can be easily reversed if necessary.