Polymyxin B, Chloramphenicol

Polymyxin B and Chloramphenicol is a combination medication used to treat severe bacterial infections. Polymyxin B is an antibiotic that works by disrupting the bacterial cell membrane, leading to the death of the bacteria. Chloramphenicol, on the other hand, is a bacteriostatic antibiotic that inhibits bacterial protein synthesis, preventing bacterial growth and replication.
This combination medication is primarily used for treating serious infections caused by bacteria that are resistant to other antibiotics. The use of this medication should be limited due to the potential side effects and risks associated with chloramphenicol, such as bone marrow suppression and aplastic anemia.
Before using Polymyxin B and Chloramphenicol, inform your healthcare provider of any pre-existing medical conditions, allergies, or current medications to ensure the safe and effective use of this medication. Regular monitoring of blood cell counts is necessary to detect any adverse effects and to adjust the treatment accordingly.