Didanosine

Didanosine, also known as ddI, is an antiretroviral medication used in the treatment of HIV/AIDS. It works by inhibiting the reverse transcriptase enzyme, which is essential for the replication of the HIV virus within the body. By blocking this enzyme, didanosine prevents the virus from multiplying, helping to slow down the progression of HIV and improving the overall health of individuals living with the condition.
Didanosine is often prescribed as a part of a combination therapy, alongside other antiretroviral drugs such as nucleoside reverse transcriptase inhibitors (NRTIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs). This approach, known as highly active antiretroviral therapy (HAART), can significantly reduce the viral load in the bloodstream and boost the immune system of HIV-positive individuals.
Didanosine is available in various forms, including oral tablets, oral powder, and intravenous injection. The choice of formulation depends on the individual’s specific needs and the advice of their healthcare professional. Follow the prescribed dosage and schedule, as well as any dietary or other instructions provided by the healthcare team.
While didanosine has been shown to be effective in managing HIV/AIDS, it may cause side effects in some patients. Common side effects include gastrointestinal issues such as nausea, vomiting, diarrhea, and abdominal pain. More severe side effects, including lactic acidosis and pancreatitis, are rare but possible. Patients should report any adverse reactions to their healthcare provider, who can then determine the most appropriate course of action.